So I just downloaded the PXSX2 emulator for Mac and installed it, but when I insert the PS2 game into my DVD ROM drive on my MacBook, nothing happens. Does anyone know of any way I could get this thing open and ready to play? I'm new at this so forgive me for sounding like an idiot.

this is posted about frequently, AND THE SEARCH FUNCTION REGISTERS HITS.

VBA-M

In case you haven't understood Squall's sarcasm : He is telling you to use the search function of the forum.
If you don't know how to search for something on a forum, go to the nearest shop and buy yourself some IQ bags (the more the better).

pcsx2 mac version can't run form disc, you need to save your ps2 discs as iso. theres a good thread somewhere on how to dump it from disc to iso. i would do as these guys have told you and use the search function to find that thread or any similar thread.