I play FF XII PAL, and FPS ranges from 30 to 50.

So i want to use frameskipping option. Every skip option i tried wasnt playable at all. I've tried turning all the speedhacks on and off, nothing. Any suggestions?

System conf:
AMD Athlon X2 64 4400+ (overclocked 2,2->2,8 GHz)
2 Gb RAM
Vista 64
Radeon 3850 (overclocked to 3870)
GS DX10

Maybe move to Vista 32/XP? maybe use some underground graph. plugin? is there any secret VU Skip setting?

what settings do you have it at, like what cpu / advance settings / plugins

CPU: MTGS, EERec, VU0rec, VU1rec all on
Advanced: EE recs Nearest, Flush, Denormals on
VU Recs Chop/ Zero, Flush on, Denorm off
GSdx13: Direct3D 10, D3D 1024*1024, Texture filtering on
SPU2ghz: no interpolation, XAudio 2 output, time stretch

I think he is asking for you Skip/VU Skip settings too

tried 0/0, 1/1, 2/2, 3/2, etc. All the same

That strange, my amd x2 OC. 3.1working fine with Vu skip. Setting 60, 50, 3, 7 in my config. Great help to play game suekoden V.

Some games simply do not run very well with Frameskip or VU Skip. There are some fairly complicated things games can do with the PS2's video framebuffers and stuff, and skipping frames will break those games pretty badly -- major herky jerkys, missing geometry, and sometimes no updates at all. FFXII happens to be a game that doesn't frameskip well. There's not much we can do about it at this time.