Try the following:
Make sure you have the Latest SVN
• Open PCSX2, go to Config, Emulation Settings.
• On the bottom-left of the dialog, there is a Preset check box, tick it, and select Safe
then click apply.
• Uncheck the Preset check box, and scroll to Speedhacks, then find the MTVU hack (bottom third on the right) and tick it, then click apply and ok.
In GSdx make sure you've everything set to default, and the resolution on native, then you can increase afterwards, if you have gotten the game running at full speed.
If that doesn't work, your system can't handle it i'm afraid.