pcsx2 0.9.6
Any of the sounds plugins.
GSdx 1650
CDVDolio 1617

its not really that bad but just so people are aware.
after like about 20 to 25 minutes the sound would turn into screeching noises.
I might just end up deleting this post if i find out the problem i have not tryed messing around to fix it but if i find out how to fix it ill post back in the screen shots thread for the settings

are you using saved states?
try loading from memcard instead if that's the case.

i believe bositman said he tested the game for an hour once, and i think he would have mentioned the sound turning to screeching noises after 20 minutes.

i never use save states
save states usually have bugs like this happen almost immediately, this is different.

this problem didnt happen for a few days of playing but after a few fmv seen's the sound i think seem to get all mixed up and the turned into screeching sounds

i havnt changed any setting on anything so i donno yet but im getting there