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this is my problem. i need help. and please upload any possible information what i did wrong.

i added bios files. and another problem. i'm running windows vista 64 bit. so i have a recovery drive. so my dvd drive is E:

and psx2 is not taking the confirguration of the E: drive.

i'm trying to also make memory cards

My PCSX2 is on drive E and I'm not having any problems.

Make sure you right click and run the game under admin mode. You can also try downloading and trying the latest beta (1474) and see if you still have the problem with it.

Huh?? Just configure the CDVD plugin to the drive letter of your dvd-rom

got it thank you