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Metal Gear Solid 2: Substance (USA) won't start
Since the old thread was closed, I'll try with another one without speaking about anything illecit.

I'm trying to load the iso with the isobooter, but the screen remains black, and the console is stuck on "isofile: searching for layer 1...".

After that, I have to manually close the process because the program freezes.

I also tried to mount the image with daemon tools and then make a full start from the menu, but it looks like no disc can be found in the ps2. I only see the memory cards.

I'm using an USA BIOS. My specs are

HD6950 (2GB)

I'm using the default settings, dx11 mode and native resolution.

Anyone can help?
Thanks in advance.

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No support for downloaded games.
CPU : I7 2600K Oc'ed @ 4.2Ghz
Mobo : Intel P67 southbridge
GPU : NVIDIA Geforce GTX 750 Ti
RAM : 6 Go

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