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is there a way to launch each game with a different configuration, eg different speedhacks, video resolution etc, even by creating a batch file with command line parameters?

Is there a frontend for that matter?

Main reason is that I keep forgetting which game needs this or that parameter to run smoothly and it makes things confusing and time consuming.

Or do I have to make multiple PCSX2 folders for each game that has specific needs?

Or else there is the option to save a text file which describes each games parameters to set those manually

here this SW will do what you want http://forums.pcsx2.net/Thread-PCSX2-Profile-Manager

This is answered in the F.A.Q.
Look in the Useful Links.

Thanks