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The only CDVDRom option that will allow the emulator to run is the CDVDNull Driver and when I use this and click Run CD/DVD, it plays the start 'Sony Computer Entertainment' bit but won't start the actual game. You can select the memory cards but can't get past there. The game I'm using is Ratchet and Clank 3 which is compatible. Please help

change the run cdvd menu to iso instead of plugin

How do I do that?

You click CDVD on the menu bar (sits between File and Config) and select iso

Ok thanks