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I have a windows vista and i've reviewed the requirements of the running specifications and see that i meet all of the standards. However, every time I use the emulator, i go through a fail routine. Start, pcsx2 needs to be configured, then i configure it. then it says "could not load GS plugins 'plugins': <NULL>. then takes me back to configure. then i reconfigure it and then it runs to the initiating screen or the menu. then i go into the tool bar and click run then it tells me an error that it can't read memory card 1 and 2, then it says Error creating bios etc.
can anyone please tell me what is happening

run it in administrator mode or turn off UAC

Also don't use DX10 Hardware mode if you don't have a DX10 capable graphics card.